Two Current Issues

Clopidogrel Resistance: Current Issues

Antiplatelet agents are mainly used in the prevention and management of atherothrombotic complications. Dual antiplatelet therapy, combining aspirin and clopidogrel, is the standard care for patients having acute coronary syndromes or undergoing percutaneous coronary intervention according to the current ACC/AHA and ESC guidelines. But in spite of administration of dual antiplatelet therapy, so...

Current Issues in Cancer

In the narrowest sense radiotherapy is a treatment almost exclusively used in managing cancer and based on the use of ionising radiation. In practice, however, the scope of the subject is broad (box 1) as management decisions relating to cancer must be made in the context of a thorough appraisal of the tumour and patient. Tumours are characterised by histogenesis and morphology, and, increasing...

Current Issues for Inflation

Most inflation models create a lot of gravitinos I will focus on papers that appeared in 1999, building on a fairly comprehensive review 1 of earlier work, and starting with gravitino creation. Gravitinos are created at reheating by thermal collisions . If the gravitino mass m3/2 is of order 100GeV, as in gravity-mediated models of SUSY breaking, these gravitinos upset nucleosynthesis unless γT...

Ototoxicity: Current Issues.

Current issues in perinatal epidemiology.

The main national data sources for perinatal epidemiology are birth and death certificates, yet routinely linked birth and death certificate data are still not available in the U.S. Completeness and quality of the reporting of perinatal events should be considered in examining trends over time and between jurisdictions. The U.S. has experienced a marked decline in its infant mortality rate, but...